Transplant Crossmatch

What is transplant crossmatch?

The gold standard test for decision to transplant is the complement dependent cytotoxicity (CDC) crossmatch. At the Rogosin Institute, we routinely perform CDC to help our patients find donors with the specific criteria that will ensure their transplant is successful. Our experienced staff has offered this service for many years and has led the way in offering the best possible donor compatibility testing for our patients in the New York City Metropolitan Area and beyond.

In addition, the Rogosin Institute performs crossmatches using a laser technology based flow cytometer to detect low levels of donor specific antibodies which may place the recipient at increased risk for acute rejection episodes.

Why is transplant crossmatching used?

Each of our kidney transplant recipient patients are required to undergo a prospective CDC crossmatch prior to the transplant. This helps to improve the success rate for the kidney transplant and ensure that the donor is a suitable candidate.

What does transplant crossmatch for kidney transplant involve?

The crossmatch test is an important stage of the kidney transplantation that is performed just before the transplant surgery is underway. This type of test is done by mixing together blood from both the kidney donor and kidney recipient. Then, the mixture is observed to see how the recipient’s cells interact with the donor cells. If the recipient’s cells attack the donor cells, a kidney transplant cannot be performed. If the recipient’s cells do not attack the donor cells, the crossmatch is considered negative, the donor is a match, and the process of transplantation can continue.

What are the benefits of using transplant crossmatch?

The benefits of undergoing transplant crossmatching at the Rogosin Institute in New York include the following:

  • Improved kidney transplant success rates
  • Higher likelihood of catching a non-match
  • Requires no downtime
  • Avoids unnecessary surgery and risks if donor is not a match

If you are interested in transplant crossmatch, visit the Rogosin Institute, recognized as one of the country’s premier centers for the diagnosis and management of kidney disease. Our doctors lead the way in transplant crossmatch testing for patients in the New York Metropolitan Area and beyond. Call our office at 212.746.1578 or fill out the form on this page to schedule an appointment with us any time.