Disease
Autoimmune, Inflammatory, and Diabetic Nephropathies

Protocol Title
RENAL AID:  REpository of Novel Analytes Leading to Autoimmune, Inflammatory, and Diabetic Nephropathies 

Principal Investigator
Alan Perlman, MD

Contact Information
Alan Perlman, MD
Phone: (212) 746-1580
Email: alp9021@nyp.org

Study Status
Open for enrollment

Brief Summary of Protocol
The purpose of this research biorepository study is to collect demographic, clinical, biochemical, histological, and genetic (RNA) data and samples from a large population of subjects with a variety of renal disease states, including diabetic, inflammatory, autoimmune and transplant related renal conditions, in order to assess for factors that may be associated with the progression of disease, the incidence of complications, (including renal failure), and the responses to therapy.  In addition, the biorepository will include the collection of data and samples from control subjects without established renal disease.

This study will provide an opportunity to compare data from various disease states with the objective of determining clinical and biological factors that predict disease progression, response to therapy and identify discriminating non-invasive clinical and biological features that predict renal biopsy findings. 

Key eligibility:
Males or females, at least 18 years of age and if you:
  - Require an initial kidney biopsy for medical necessity; or   
  - Previously had a kidney biopsy and the tissue is not stored in this biorepository; or
  - Have diabetes and kidney disease and have not had a kidney biopsy; or   
  - Had a kidney transplant and require a transplant biopsy 

Treatment Overview (Potential Benefits)
There is no guarantee that subjects will benefit personally from this study. Knowledge gained from RENAL AID may benefit subjects and others in the future.

IRB Information
Weill Cornell Medical College
Protocol # 1207012648

Sponsor
The Rogosin Institute

ClinicalTrials.gov Identifier:  NCT01802034